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The Lagging Strand

Monday, June 22, 2009

Folate mediated one-carbon metabolism

Nuclear translocation of dihydrofolate reductase is not a pre-requisite for DNA damage induced apoptosis. Yuan TT, Huang Y, Zhou CX, Yu Y, Wang LS, Zhuang HY, Chen GQ. Apoptosis. 2009 May;14(5):699-710.

SHMT1 and SHMT2 are functionally redundant in nuclear De novo thymidylate biosynthesis. Anderson DD, Stover PJ. PLoS One. 2009 Jun 9;4(6):e5839.

Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase. Anderson DD, Woeller CF, Stover PJ. Clin Chem Lab Med. 2007;45(12):1760-3.

Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway. Woeller CF, Anderson DD, Szebenyi DM, Stover PJ. J Biol Chem. 2007 Jun 15;282(24):17623-31. Epub 2007 Apr 19.


Posted by Noscene at 9:26 PM

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